Marquette University
Press Release

Marquette researcher receives grant to educate and treat patients with brittle bone disease

The research will consist of two clinical projects.

By - Aug 7th, 2015 10:24 am

MILWAUKEE – Dr. Gerald Harris, professor of biomedical engineering and director of the Orthopedic and Rehabilitation Engineering Center (OREC) at Marquette, received a $500,000, five-year grant from the National Institutes of Health. The award is part of the Brittle Bone Disorders Consortium of the Rare Disease Clinical Research Network, which is working to advance knowledge and treatment of children and adults with all genetic forms of brittle bone disease.

Scholars are researching more than 13 genetic conditions that contribute to the Osteogenesis Imperfecta phenotype, also known as “brittle bone disease,” which is a genetic bone disorder that often results in fractures. A collection of associated non-skeletal symptoms that include dental, respiratory and cardiac problems, also make up the condition.

The research will consist of two clinical projects. The first is a longitudinal study of OI focused on correlating genotype to phenotype, the natural history of vertebral fractures, scoliosis in severe OI, pregnancy in OI and craniofacial/dental features in severe OI. The second project will test different treatment doses against one another to determine which is most effective.

Harris, with co-partner Dr. Peter Smith from Shriners Hospital for Children in Chicago and the Osteogenesis Imperfecta Foundation (OIF), will help establish the Brittle Bones Disorders Rare Disease Clinical Research Consortium, which comprises eight sites in the U.S. and Canada.

The Osteogenesis Imperfecta Foundation will establish a fellowship for clinical research training, a clinical bone research training workshop and develop a web-based “tool box” for primary health care providers to extend knowledge to their patients.

Mentioned in This Press Release

Organizations:

Recent Press Releases by Marquette University

Marquette supply chain management students win national case competition

Team bests 10 other universities at annual Arizona State contest

Marquette’s College of Health Sciences Receives $1 Million Estate Gift

Donation will establish the Michael and Jeanne Schmitz Family Depression Research Fund

Law professor Ellis, ACLU voting rights advocate McGrath go ‘On the Issues’ at Marquette Law School

Since the 2010 election, more than 20 states have enacted new voting laws.

Leave a Reply

Your email address will not be published. Required fields are marked *